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Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Shape-memory polymers as a technology platform for biomedical applications.

Andreas Lendlein¹, Marc Behl, Bernhard Hiebl

¹Centre for Biomaterial Development, Institute of Polymer Research, GKSS Research Centre Geesthacht GmbH, Kantstr. 55, Teltow, Germany. andreas.lendlein@gkss.de

Expert Review of Medical Devices

|April 28, 2010

Summary

This summary is machine-generated.

Shape-memory polymers offer tailored functionalities for advanced medical devices and drug delivery systems. This technology enables novel implants with controlled movement, mechanical properties, and biocompatibility for future clinical use.

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Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

Published on: January 8, 2014

Area of Science:

Biomaterials Science
Polymer Chemistry
Medical Device Engineering

Background:

Polymeric materials are essential for medical devices and drug delivery.
Current applications require polymers with specific functionalities like mechanical properties or active movement for minimally invasive implants.
Shape-memory polymers (SMPs) present a promising technology platform to meet these demands.

Purpose of the Study:

To review the principles, compositions, and architectures of shape-memory polymers.
To illustrate the potential of SMPs as a technology platform for multifunctional medical devices.
To highlight the development of novel medical devices utilizing SMPs for near-future clinical evaluation.

Main Methods:

Comprehensive review of scientific literature.
Analysis of patent literature.
Examination of SMP principles, compositions, and architectures.

Main Results:

SMPs enable the tailored design of multifunctionality in polymers.
Key functionalities include controlled implant movement, specific mechanical properties, sterilization compatibility, biodegradability, biocompatibility, and controlled drug release.
SMP technology facilitates the creation of novel medical devices.

Conclusions:

Shape-memory polymers represent a versatile technology platform for advanced medical applications.
SMPs can be engineered to provide a range of critical functionalities for medical devices and drug delivery systems.
The development of SMP-based medical devices is progressing towards clinical evaluation.