Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Circulating immune complexes in tuberculosis.

A Arora1, J P Wali, P Seth

  • 1Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi.

Singapore Medical Journal
|April 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic markers, quality of life (QoL) and value of health (V-He) in advanced biliary cancers (ABC) treated with second-line active symptom control (ASC) alone or ASC with oxaliplatin-5-FU chemotherapy (ASC + FOLFOX) in the randomised phase III, multicentre, open-label ABC-06 clinical trial.

ESMO open·2026
Same author

Search for Light Pseudoscalar Bosons, Pair-Produced in Higgs Boson Decays in the Four-Electron Final State in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

First Evidence for Mixing-Induced CP Violation in B_{s}^{0}→J/ψϕ(1020) Decays in pp Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

Observation of Suppressed Charged-Particle Production in Ultrarelativistic Oxygen-Oxygen Collisions.

Physical review letters·2026
Same author

Measurement of D^{0} Meson Photoproduction in Ultraperipheral Heavy Ion Collisions.

Physical review letters·2026
Same author

Covid-19 and Its Arthritic Footprint: Clinical, Laboratory and Imaging Insights from a Cross Sectional Study in a Tertiary Center in Telangana.

Mymensingh medical journal : MMJ·2026
Same journal

Response to comments on: Diagnostic classification of dermatomyositis with and without electrodiagnostic study: real-world clinical practice.

Singapore medical journal·2026
Same journal

Comments on: Diagnostic classification of dermatomyositis with and without electrodiagnostic study: real-world clinical practice.

Singapore medical journal·2026
Same journal

Computed tomographic evaluation of bronchiolitis: unravelling the multifaceted spectrum of airways and pulmonary abnormalities.

Singapore medical journal·2026
Same journal

Approach to facial pain.

Singapore medical journal·2026
Same journal

Glioblastoma: current challenges and future horizons.

Singapore medical journal·2026
Same journal

The role of public health specialists in tertiary hospitals in Singapore.

Singapore medical journal·2026
See all related articles

Circulating immune complexes (CICs) are elevated in most active tuberculosis patients. Treatment significantly reduced CICs levels, suggesting their role in monitoring tuberculosis activity.

Area of Science:

  • Immunology
  • Infectious Diseases
  • Biochemistry

Background:

  • Tuberculosis (TB) remains a significant global health challenge.
  • The role of immune responses in TB pathogenesis is complex.
  • Biomarkers for monitoring TB activity are crucial for effective management.

Purpose of the Study:

  • To investigate the correlation between circulating immune complexes (CICs) and active tuberculosis.
  • To assess the impact of anti-tuberculosis drug treatment on CICs levels.

Main Methods:

  • Sera from 75 active tuberculosis patients and 25 controls were analyzed for CICs.
  • The polyethylene glycol (PEG) precipitation method was employed for CICs quantification.
  • CICs levels were monitored in 25 patients undergoing drug treatment.

Related Experiment Videos

Main Results:

  • Elevated CICs levels were detected in 96% of untreated active tuberculosis patients.
  • CICs levels in patients significantly decreased following drug treatment.
  • By the end of treatment, 64% of patients showed CICs levels comparable to control subjects.

Conclusions:

  • Circulating immune complexes (CICs) are significantly elevated in active tuberculosis.
  • Decreased CICs levels correlate with successful tuberculosis treatment.
  • CICs may serve as a potential biomarker for monitoring tuberculosis activity and treatment response.