Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Tilted Least Squares Robust Estimators.

Automatica : the journal of IFAC, the International Federation of Automatic Control·2025

Same author

Identification of Sparse Volterra Systems: An Almost Orthogonal Matching Pursuit Approach.

IEEE transactions on automatic control·2022

Same author

Persistence of Excitation for Identifying Switched Linear Systems.

Automatica : the journal of IFAC, the International Federation of Automatic Control·2022

Same author

Vocal pattern detection of depression among older adults.

International journal of mental health nursing·2019

Same author

Extracellular vesicles derived from bone marrow mesenchymal stem cells attenuate dextran sodium sulfate-induced ulcerative colitis by promoting M2 macrophage polarization.

International immunopharmacology·2019

Same author

Light-activated "cycle-reversible intramolecular charge transfer" fluorescent probe: monitoring of pHi trace change induced by UV light in programmed cell death.

Chemical communications (Cambridge, England)·2019

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Published on: December 9, 2021

Dose reduction with adaptive bolus chasing computed tomography angiography.

Zhijun Cai¹, Er-Wei Bai, Ge Wang

¹Department of Electrical and Computer Engineering, University of Iowa, Iowa City, IA 52242, USA.

Journal of X-Ray Science and Technology

|April 28, 2010

Summary

This study introduces a novel dose reduction method for Computed Tomography Angiography (CTA) by adaptively tracking contrast flow. The technique successfully reduced effective radiation dose by 39% while maintaining image quality for diagnosis.

More Related Videos

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Related Experiment Videos

Last Updated: Jun 13, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Published on: December 9, 2021

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Area of Science:

Medical Imaging
Radiology
Biomedical Engineering

Background:

Computed Tomography (CT) is a vital diagnostic tool, but increasing scan frequency raises concerns about radiation exposure.
Reducing radiation dose in CT while preserving diagnostic image quality is a critical research challenge.

Purpose of the Study:

To develop and evaluate a dose reduction strategy for CT Angiography (CTA) using adaptive bolus chasing.
To maintain diagnostic image quality and contrast-to-noise ratio (CNR) in CTA scans with reduced radiation.

Main Methods:

Implementation of adaptive bolus chasing techniques to track contrast agent flow in blood vessels.
Online modulation of tube current and collimator width to optimize radiation dose.
Numerical experiments on Digital Subtraction Angiography (DSA) datasets for validation.

Main Results:

The proposed method achieved an effective radiation dose reduction of approximately 39%.
The adaptive bolus chasing approach successfully maintained the contrast-to-noise ratio (CNR) of blood vessels.
Demonstrated feasibility of dose reduction without compromising diagnostic interpretability.

Conclusions:

Adaptive bolus chasing CTA offers a promising approach for significant radiation dose reduction in medical imaging.
This method balances the need for effective diagnosis with patient safety concerns regarding radiation exposure.
Further clinical validation is warranted to confirm the efficacy and safety of this technique.