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Updated: Jun 13, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Arterial stiffness in the young: assessment, determinants, and implications
1Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.
Arterial stiffness, the rigidity of artery walls, is increasingly recognized as a risk factor for cardiovascular disease in children. Early detection through noninvasive methods may allow for timely interventions.
Area of Science:
- Cardiovascular Physiology
- Pediatric Cardiology
Background:
- Arterial stiffness, or the rigidity of artery walls, impacts left ventricular afterload and ventricular-arterial coupling.
- In adults, arterial stiffness is a recognized marker and risk factor for cardiovascular morbidity and mortality.
- Noninvasive methods for assessing arterial stiffness are increasingly used in pediatric populations.
Purpose of the Study:
- To explore the phenomenon and significance of arterial stiffening in children and adolescents.
- To identify childhood factors and conditions associated with arterial stiffening.
- To understand the functional implications of arterial stiffening on the left ventricle.
Main Methods:
- Utilizing noninvasive techniques to measure local, segmental, and systemic arterial stiffness.
- Reviewing childhood factors and conditions linked to arterial stiffening.
- Analyzing the functional impact of arterial stiffness on left ventricular structure and function.
Main Results:
- The association of arterial stiffening with various childhood conditions has expanded, including traditional cardiovascular risk factors, prenatal growth restriction, vasculitides, and congenital heart disease.
- Arterial stiffening in youth has functional implications on left ventricular energetic efficiency, structure, and function.
- Early identification of arterial dysfunction in childhood is emerging as a potential window for intervention.
Conclusions:
- Arterial stiffening is a significant finding in pediatric populations, associated with numerous health conditions.
- Early detection of arterial stiffness in children may offer opportunities for intervention.
- Further longitudinal studies are needed to confirm clinical benefits of improving arterial function in pediatric populations.
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