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Reconstruct Human Retinoblastoma In Vitro
Published on: October 11, 2022
Compliance in retinoblastoma
Sameer Bakhshi1, Shikha Gupta, Varun Gogia
1Department of Medical Oncology, Dr. B. R. A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India. sambakh@hotmail.com
Indian Journal of Pediatrics
|April 28, 2010
Summary
Compliance with retinoblastoma treatment is low, particularly in Asian countries. Further prospective studies are needed to identify causes and improve patient outcomes for this advanced eye cancer.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Public Health
Background:
- Retinoblastoma is a common intraocular malignancy in children.
- Compliance with treatment is crucial for successful outcomes.
- Limited data exists on compliance factors in Asian populations.
Purpose of the Study:
- To evaluate treatment compliance in retinoblastoma patients.
- To analyze sociodemographic factors influencing compliance.
- To compare retinoblastoma compliance with other cancers.
Main Methods:
- Retrospective descriptive study of 177 retinoblastoma patients (June 2003-February 2007).
- Data collected on sociodemographics, symptom duration, and treatment adherence.
- Follow-up rates compared with Hodgkin's lymphoma, acute myeloid leukemia, and non-Hodgkin's lymphoma.
Main Results:
- Median symptom duration was 7.2 months.
- Adequate therapy was received by 84/141 (59.6%) patients.
- Follow-up was achieved in only 47.5% of cases, significantly lower than other cancers.
- Enucleation was accepted in 92.5% of indicated eyes.
- No sociodemographic factors significantly impacted compliance.
Conclusions:
- This study highlights poor compliance in retinoblastoma patients in Asia.
- Low follow-up rates necessitate further investigation.
- Prospective studies are recommended to determine reasons for poor compliance and improve ocular salvage rates.
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