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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Transanal one-stage endorectal pull-through for Hirschsprung disease: experiences with 51 newborn patients
Pham Anh Vũ1, Ho Huu Thien, Pham Nhu Hiep
1Department of Surgery, Hue College of Medicine and Pharmacy, Hue, Vietnam. phamanhvu@hotmail.com
Introduction:
Transanal one-stage endorectal pull-through (TOSEPT) has been presented as the most recent progression in the treatment of Hirschsprung's disease (HD), which may be able to replace various previous techniques. This prospective study was designed to evaluate the efficacy and probable complications of this procedure in management of newborns with HD.
Materials And Methods:
Fifty-one newborns (33 boys and 18 girls) underwent TOSEPT; all after being diagnosed by barium enema and rectal biopsy over a 52-month period. All patients were followed-up up from 6 to 48 months after hospital discharge.
Results:
There was no per-operative complication. Laparotomy was necessary in five children (9.8%). Average length of aganglionosis segment was 13.9 cm +/- 6.0 cm. Mean postoperative hospitalization time was 7.1 days. TOSEPT was redone in two patients (3.9%) because of aganglionosis segment remaining. After 6-48 months of follow-up, all children have been well now.
Conclusion:
Our data suggested that TOSEPT is efficacious and safe in the management of newborn with HD.
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