Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Esophageal Achalasia

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...

Chronic Obstructive Pulmonary Disease II: Emphysema

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.

Epistaxis

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...

Esophageal Strictures-I: Introduction

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Italian translation, cross-cultural adaptation and validation of the Mayo Clinic Vestibular Schwannoma Quality of Life (VSQOL) Index.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2026

Same author

Italian validation of the ENS6Q: a disease-specific questionnaire for empty nose syndrome.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2026

Same author

Revisiting Eustachian Tube Anatomy and Physiology.

Otolaryngologic clinics of North America·2026

Same author

Impact of Tongue Tip Reconstruction on Articulatory Performance After Major Tongue Resections: Evidence From a Multicentric Study.

Microsurgery·2026

Same author

The use of centrifugated autologous lipoaspirate in the endoscopic management of idiopathic subglottic stenosis: results from a retrospective non-randomized study.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2026

Same author

Human versus AI in audiological practice: A comparative evaluation of ChatGPT and physician treatment decisions in idiopathic sudden sensorineural hearing loss.

PloS one·2026

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

Published on: April 28, 2023

Selective epitympanic dysventilation syndrome.

Daniele Marchioni¹, Matteo Alicandri-Ciufelli, Gabriele Molteni

¹Department of Otolaryngology-Head Neck Surgery, University Hospital of Modena, Modena, Italy.

The Laryngoscope

|April 28, 2010

Summary

Normal eustachian tube function may not be enough for middle ear aeration. An open tympanic isthmus or incomplete tensor fold is crucial for epitympanic recess ventilation, suggesting a selective epitympanic dysventilation syndrome.

More Related Videos

Endaural Endoscopic Atticoantrotomy (Retrograde Mastoidectomy) using a Constant Suction Bone-drilling Technique

Endaural Endoscopic Atticoantrotomy (Retrograde Mastoidectomy) using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

Related Experiment Videos

Last Updated: Jun 13, 2026

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

Published on: April 28, 2023

Endaural Endoscopic Atticoantrotomy (Retrograde Mastoidectomy) using a Constant Suction Bone-drilling Technique

Endaural Endoscopic Atticoantrotomy (Retrograde Mastoidectomy) using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

Area of Science:

Otolaryngology
Middle Ear Pathophysiology
Surgical Anatomy

Background:

Middle ear aeration is linked to eustachian tube (ET) function.
Other anatomical factors may influence middle ear ventilation, especially the epitympanum.

Purpose of the Study:

To investigate the role of anatomical factors in middle ear ventilation beyond eustachian tube function.
To identify potential causes of selective epitympanic dysventilation.

Main Methods:

Prospective case series with retrospective comparison.
Eight patients with attic retraction pockets or cholesteatoma and normal tubal function underwent endoscopic surgery.
Anatomical findings, focusing on middle ear folds, were collected and compared to a control group.

Main Results:

A statistically significant higher prevalence of isthmus blockage with a complete tensor fold was observed in patients with middle ear pathology (P = .001).

Conclusions:

A selective epitympanic dysventilation syndrome is hypothesized.
Normal eustachian tube function alone may be insufficient for adequate middle ear ventilation.
An open tympanic isthmus and/or incomplete tensor fold appear necessary for epitympanic recess ventilation.