Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Chain entanglements enable regeneration of high-performance thermosets.

Nature materials·2026

Same author

Mechanistic Origins of Polydicyclopentadiene Oxidation.

Journal of the American Chemical Society·2026

Same author

Ultrasound-driven mechanophore activation in living plants.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Single-Molecule Electron Transport in Peptoids.

The journal of physical chemistry. B·2026

Same author

Aromatic Amide Foldamers Show Conformation-Dependent Electronic Properties.

Chemphyschem : a European journal of chemical physics and physical chemistry·2025

Same author

Tuning the Ultimate Strain of Single and Double Network Gels Through Reactive Strand Extension.

ACS central science·2025

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

Published on: December 23, 2016

Robust, double-walled microcapsules for self-healing polymeric materials.

Mary M Caruso¹, Benjamin J Blaiszik, Henghua Jin

¹Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

ACS Applied Materials & Interfaces

|April 29, 2010

Summary

This study introduces robust double-walled polyurethane/poly(urea-formaldehyde) microcapsules for self-healing materials. The modified encapsulation enhances shell thickness and thermal stability, improving material performance.

More Related Videos

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Published on: August 28, 2015

Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids

Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids

Published on: October 13, 2021

Related Experiment Videos

Last Updated: Jun 13, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

Published on: December 23, 2016

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Published on: August 28, 2015

Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids

Microfluidic Fabrication of Core-Shell Microcapsules carrying Human Pluripotent Stem Cell Spheroids

Published on: October 13, 2021

Area of Science:

Materials Science
Polymer Chemistry

Background:

Self-healing materials require robust microcapsules for damage repair.
Standard poly(urea-formaldehyde) (UF) microcapsules have limitations in shell integrity.
Combining polyurethane (PU) with UF offers a potential route to enhanced microcapsule properties.

Purpose of the Study:

To develop and characterize double-walled polyurethane/poly(urea-formaldehyde) (PU/UF) microcapsules.
To investigate the effect of PU addition on microcapsule shell thickness and robustness.
To evaluate the thermal stability and mechanical properties of the novel PU/UF microcapsules.

Main Methods:

A modified encapsulation procedure combining PU and UF chemistries in a single step.
Preparation of PU/UF microcapsules with varying PU content in the core liquid.
Analysis of shell wall thickness via microscopy (implied).
Thermal stability assessment using comparative analysis.
Mechanical property evaluation through single-capsule compression testing.

Main Results:

The modified PU/UF encapsulation procedure successfully created robust double-walled microcapsules.
Shell wall thickness increased significantly from 200 nm (UF) to 675 nm (PU/UF) with increasing PU content.
PU/UF microcapsules exhibited enhanced thermal stability compared to standard UF microcapsules.
Single-capsule compression tests provided insights into the mechanical performance of the PU/UF capsules.

Conclusions:

The developed double-walled PU/UF microcapsules offer superior robustness and increased shell thickness.
This modified encapsulation technique is effective for enhancing microcapsule properties for self-healing applications.
The improved thermal and mechanical characteristics of PU/UF microcapsules show promise for advanced material functionalities.