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Updated: Jun 13, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
Toxic megacolon secondary to Clostridium difficile colitis. Case report
M A Sánchez-Pérez1, M Muñoz-Juárez, E Luque-de León
1Department of General Surgery at the American British Cowdray Medical Center (Centro Médico ABC), Mexico City. wfrguitarma@hotmail.com
Abstract:
The incidence and severity of Clostridium difficile colitis has markedly increased in recent years. The spectrum of Clostridium difficile infection ranges from asymptomatic colonization to fulminant colitis requiring immediate surgery. Medical therapy failure and the presence of toxic megacolon dictate urgent surgical treatment with unfortunate high mortality rates (35% to 57%). We broach herein a case of toxic megacolon secondary to colitis due to Clostridium difficile infection in which early diagnosis and prompt surgical treatment led to a successful outcome.
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