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Related Concept Videos

Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

Peptic Ulcer Disease III: Clinical Manifestations and Complications

Duodenal UlcersDuodenal ulcers are the most common form of peptic ulcer disease, presenting with chronic, intermittent epigastric pain. Pain typically appears 2–3 hours after meals, especially when the stomach is empty, often waking patients at night. It is characteristically relieved by food or antacids (“pain–food–relief”). Some patients remain asymptomatic until complications like bleeding or perforation emerge, particularly with NSAID or anticoagulant use.Gastric UlcersGastric ulcers share...

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Related Experiment Video

Updated: Jun 13, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

[Zollinger-Ellison syndrome: a case report.].

R Torres-Mansur1, M A Miranda-de León, H Zamudio-Tiburcio

  • 1Cirujano general adscrito. Servicio de Cirugía General, Hospital General Dr. Norberto Treviño Zapata. Ciudad Victoria, Tamaulipas, México. rafamansur@hotmail.com

Revista De Gastroenterologia De Mexico
|April 29, 2010
PubMed
Summary

A woman with persistent epigastric pain was diagnosed with a gastrinoma, a rare tumor causing excess gastrin. Surgical resection led to a full recovery, resolving her gastrointestinal symptoms.

Related Experiment Videos

Last Updated: Jun 13, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Area of Science:

  • Gastroenterology
  • Endocrinology
  • Surgical Oncology

Background:

  • A 42-year-old woman presented with a 3-year history of burning epigastric pain, nausea, vomiting, food intolerance, and steatorrhea.
  • Initial treatments included H2 blockers and laparoscopic cholecystectomy for cholelithiasis, which did not resolve her symptoms.

Observation:

  • The patient developed upper gastrointestinal bleeding due to severe esophagitis and gastritis, with only partial improvement from high-dose proton pump inhibitors.
  • Abdominal ultrasound revealed a pancreatic head tumor, and significantly elevated serum gastrin levels (17,251 μg/L) were detected.

Findings:

  • Surgical exploration with intraoperative ultrasound successfully localized and resected a mass in the pancreatic head.
  • Pathological examination confirmed the mass as a gastrinoma.

Implications:

  • This case highlights the diagnostic challenge of gastrinoma, particularly in the absence of typical Zollinger-Ellison syndrome features.
  • Successful surgical resection of the gastrinoma resulted in complete symptom resolution and a positive long-term outcome.