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[Progress on genes related to fetal hemoglobin quantitative trait]

Xiao-Qiang Guo1

  • 1Department of Biochemistry, Bethune Military Medical College, Shijiazhuang 050081, China. xiaoqiangguo123@163.com

Yi Chuan = Hereditas
|April 29, 2010
PubMed
Summary

High fetal hemoglobin (HbF) levels benefit anemia patients. Genes HBS1L-MYB and BCL11A on chromosomes 6q23 and 2p15 are key regulators of HbF, offering potential therapeutic targets for sickle cell disease.

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