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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Preoperative use and safety of coronary angiography for acute aortic valve infective endocarditis
Guillaume Hekimian1, Myongchan Kim, Stephanie Passefort
1Cardiology Department, APHP and University Paris, Bichat Hospital, Paris, France.
Insights
Preoperative coronary angiography (CA) in patients with aortic valve infective endocarditis (AV-IE) is safe and recommended for those with cardiovascular risk factors. This procedure did not increase mortality or worsen renal function, supporting current guidelines.
Area of Science:
- Cardiology
- Cardiac Surgery
- Infectious Diseases
Background:
- Preoperative coronary angiography (CA) is recommended for patients with acute aortic valve infective endocarditis (AV-IE) and high cardiovascular risk.
- However, evidence is limited, and risks include vegetation dislodgement and contrast-induced nephropathy.
Purpose of the Study:
- To review the use, indications, and complications of preoperative CA in patients with AV-IE.
- To evaluate the safety and impact of CA on patient outcomes.
Main Methods:
- Retrospective study of 83 patients operated on for AV-IE between January 2002 and March 2007.
- Analysis of CA use, findings, and associated complications.
Main Results:
- CA was performed preoperatively in 36 (43%) patients.
- No embolic events occurred post-CA. Preoperative CA was not associated with increased in-hospital mortality or worsening renal function.
- Patients undergoing CA tended to be healthier, but anatomical lesions were similar.
Conclusions:
- Preoperative CA can be performed safely in selected AV-IE patients with cardiovascular risk factors.
- The findings support current guidelines recommending CA before surgery in these patients.
Background:
Preoperative coronary angiography (CA) is recommended in patients with acute aortic valve infective endocarditis (AV-IE) and high cardiovascular risk profile but the level of evidence is low and its potential interest may be counterbalanced by the risk of dislodgement of vegetations and contrast-induced nephropathy.
Objective:
To review the use, indications and complication of preoperative CA in patients with AV-IE. Design Retrospective study.
Patients:
Consecutive series of 83 patients operated on for AV-IE between January 2002 and March 2007.
Results:
CA was performed in 36 (43%) patients, all but one as a preoperative test. Significant (>or=70%) lesions were observed in 10 patients and six underwent an associated coronary artery bypass graft. 47 patients were operated on without preoperative CA because of young age in 16 or recent CA in 13. Despite being theoretically indicated in all but one of the 18 remaining patients, CA was not performed because surgery as judged too urgent (eight patients) or valvular lesions were estimated as too important (10 patients). While the 35 patients with preoperative CA tended to be healthier (longer time to surgery and lower rate of urgent surgery), anatomical lesions were not different (rate of severe regurgitation, periannular complications and vegetation size, all p>0.20). No embolic event occurred after CA and preoperative CA was not associated with increased in-hospital mortality (p=0.80) or worsening renal function (p=0.93).
Conclusion:
Preoperative CA can be performed at low risk in selected patients with AV-IE and should be considered before surgery in patients with cardiovascular risk factors. Our results support current guidelines.
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