Related Experiment Video
Updated: Jun 13, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Hypertelorism and an unclear sinonasal mass]
C Koll1, J Schipper, T K Hoffmann
1Hals-Nasen-Ohren-Klinik, Universität Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Deutschland. Caroline.Koll@med.uni-duesseldorf.de
Abstract:
An 88-year-old female patient presented at our ENT clinic following syncope for consultation regarding dyspnea. Nasal breathing and olfactory function had been absent for several decades. The nose was distended and showed a livid red, smooth invasive mass. Childhood onset of nasal polyposis was reported. In addition, hypertelorism and bilateral epiphora were present. Although the patient declined treatment, it was possible to establish the clinical diagnosis of a Woakes' syndrome.
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