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Pancreatic disease in children and adolescents

Christopher D Jolley1

  • 1Department of Pediatrics, The University of Florida, Gainesville, FL 32610-0296, USA. jollecd@peds.ufl.edu

Current Gastroenterology Reports
|April 29, 2010
PubMed

Insights

Childhood pancreatic disorders, though rare, can be severe, encompassing congenital anomalies and acquired conditions like drug-induced pancreatitis. Genetics significantly influences pediatric pancreatic diseases, differing from adult causes.

Area of Science:

  • Pediatric Gastroenterology
  • Pancreatology
  • Genetics

Background:

  • Childhood pancreatic disorders are rare but can lead to severe illness.
  • The range of these disorders is broad, including congenital anomalies and acquired conditions.
  • Genetics plays a significant role in pediatric pancreatic diseases, contrasting with adult causes like alcohol consumption.

Purpose of the Study:

  • To review the spectrum of childhood pancreatic disorders.
  • To highlight the genetic influences in pediatric pancreatic diseases.
  • To discuss similarities and differences between pediatric and adult pancreatic disorders.

Main Methods:

  • Literature review of childhood pancreatic disorders.
  • Analysis of genetic factors in pediatric pancreatic diseases.
  • Comparison of pediatric and adult pancreatic disease presentations.

Main Results:

  • Childhood pancreatic disorders include congenital anomalies and acquired conditions (e.g., drug-induced pancreatitis, trauma).
  • Genetic factors are prominent in pediatric pancreatic diseases.
  • Many pancreatic disorders manifest in both pediatric and adult populations.

Conclusions:

  • Childhood pancreatic disorders require careful diagnosis and management.
  • Further research is needed on newer imaging and therapeutic endoscopy in children.
  • Understanding the genetic basis is crucial for pediatric pancreatic disease management.

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