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Updated: Jun 13, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

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Published on: June 16, 2020

Imaging lung disease in systemic sclerosis.

Diane Strollo1, Jonathan Goldin

  • 1Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA. strollodc@upmc.edu

Current Rheumatology Reports
|April 29, 2010
PubMed
Summary
This summary is machine-generated.

Systemic sclerosis (SSc) commonly causes lung disease and pulmonary hypertension (PH). High-resolution CT scanning is vital for detecting SSc-related lung issues and guiding treatment.

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Area of Science:

  • Cardiopulmonary Medicine
  • Radiology
  • Rheumatology

Background:

  • Systemic sclerosis (SSc) frequently involves cardiopulmonary systems.
  • Scleroderma interstitial lung disease affects two-thirds of SSc patients.
  • Pulmonary hypertension (PH) occurs in 20% of SSc patients, often with severe lung disease.

Purpose of the Study:

  • To highlight the role of imaging in managing SSc-related lung disease.
  • To emphasize the importance of high-resolution CT (HRCT) in evaluating chest involvement.
  • To outline the multifaceted applications of imaging in SSc patients.

Main Methods:

  • Review of current literature and clinical practice regarding SSc.
  • Focus on the diagnostic and prognostic utility of high-resolution CT scanning.
  • Discussion of imaging's role in treatment response and efficacy assessment.

Main Results:

  • High-resolution CT is crucial for detecting and characterizing lung involvement in SSc.
  • Imaging aids in identifying patients who may benefit from specific treatments.
  • Radiological assessment is key for monitoring treatment effectiveness and excluding other conditions.

Conclusions:

  • Imaging, particularly HRCT, plays a critical role in the comprehensive management of SSc.
  • Effective use of imaging supports personalized treatment strategies for SSc patients.
  • Multimodality imaging is essential for evaluating lung disease, PH, and other thoracic abnormalities in SSc.