Related Experiment Video
Updated: Jun 13, 2026

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
Current management of hepatocellular cancer
Bernardino Rampone1, Beniamino Schiavone, Giuseppe Confuorto
1Department of Surgery, Pineta Grande Hospital, Castel Volturno, Caserta, Italy. ramponebernardino@virgilio.it
Abstract:
Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver, being the fifth most frequent cancer worldwide. It usually occurs in the setting of chronic liver disease and has a poor prognosis if untreated. Following the diagnosis, this disease requires multidisciplinary management. Orthotopic liver transplantation is theoretically the best treatment for early, unresectable HCC. However, the major practical obstacle is the extreme shortage of organs, which makes this a practical option only in selected patients. In this report we describe new advancements in diagnosis, classification, and treatment that have emerged in the field of HCC in recent years.
Related Concept Videos
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Treatment Resistent Cancers
Treatment Resistant Cancers

