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Coronary intervention in patients with acute coronary syndrome: does every culprit lesion require revascularization?

Sripal Bangalore1, David P Faxon

  • 1Division of Cardiology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 0BC3-Room 012P, 1620 Tremont Street, Boston, MA 02120, USA.

Current Cardiology Reports
|April 29, 2010
PubMed

Insights

Patients with acute coronary syndromes and multivessel disease face higher risks. This review examines evidence on the safety and efficacy of multivessel revascularization for these complex cardiovascular cases.

Area of Science:

  • Cardiology
  • Interventional Cardiology

Background:

  • 30-60% of acute coronary syndrome (ACS) patients have multivessel disease (MVD).
  • MVD in ACS correlates with increased cardiovascular morbidity and mortality compared to single-vessel disease.
  • Despite advances in reperfusion and antiplatelet therapy, optimal MVD treatment in ACS remains debated.

Purpose of the Study:

  • To review the current evidence regarding the safety and efficacy of multivessel revascularization in patients with acute coronary syndromes and MVD.

Main Methods:

  • Systematic review of existing literature.
  • Analysis of studies reporting on safety and efficacy outcomes of multivessel revascularization in ACS patients.

Main Results:

  • Multivessel revascularization in ACS is associated with specific safety and efficacy profiles.
  • Evidence synthesis aims to clarify the benefits and risks in this high-risk patient population.

Conclusions:

  • Further consensus is needed on the optimal management strategy for MVD in ACS.
  • This review provides a foundation for understanding the role of multivessel revascularization in ACS treatment.

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