Related Experiment Video
Updated: Jun 13, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Is minimally invasive surgery appropriate for small differentiated thyroid carcinomas?
Massimo Ruggieri1, Antonio Zullino, Andrea Straniero
1Department of Surgery Francesco Durante, Sapienza University, Viale del Policlinico, 00161 Rome, Italy.
Purpose:
To retrospectively evaluate the surgical completeness of minimally invasive total thyroidectomy for small (<20 mm) differentiated thyroid carcinoma (DTC).
Methods:
The subjects of this study were 30 patients who underwent minimally invasive total thyroidectomy as a single procedure. We registered the following postoperative measurements in the LT4 withdrawal period: serum thyroglobulin level, 6-h radioiodine uptake diagnostic test results, and neck ultrasound (US) findings.
Results:
The mean serum thyroglobulin level was 4.99 +/- 4.67 ng/ml, the mean radioiodine uptake diagnostic test after 6 h was 3.11% +/- 2.90%, and US showed no thyroid remnant.
Conclusions:
The short-term outcome measures showed adequate resection of thyroid tissue, comparable with that reported after conventional surgery. Our findings suggest that small nodules with suspicious or malignant cytology are one of the best indications for minimally invasive surgery.

