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Updated: Jun 13, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Weight management using a meal replacement strategy in type 2 diabetes.
Osama Hamdy1, Debbie Zwiefelhofer
1Joslin Diabetes Center, Boston, MA 002215, USA. Osama.Hamdy@joslin.harvard.edu
Meal replacements (MRs) offer a feasible strategy for weight reduction in individuals with diabetes and obesity. This multidisciplinary approach requires careful blood glucose monitoring and potential medication adjustments.
Area of Science:
- Endocrinology
- Nutrition Science
- Metabolic Disorders
Background:
- Rising rates of diabetes are linked to increasing obesity prevalence.
- Weight reduction presents significant challenges for overweight and obese individuals with diabetes.
Purpose of the Study:
- To review the efficacy and application of meal replacements (MRs) for weight reduction in patients with diabetes.
- To discuss the role of MRs in both short-term and long-term weight management strategies for this population.
Main Methods:
- Analysis of clinical trials and real-world clinical practice data on MRs for diabetes patients.
- Evaluation of the nutritional completeness and acceptability of commercial MRs.
- Consideration of the multidisciplinary approach involving structured dietary intervention.
Main Results:
- Weight reduction using MRs is achievable for patients with diabetes within a multidisciplinary framework.
- Nutritionally complete MRs support initial weight loss and maintenance due to their adequacy.
- Close blood glucose monitoring and medication adjustment are crucial for patients using MRs.
Conclusions:
- Meal replacements are a viable tool for managing weight in diabetic individuals.
- The use of MRs necessitates careful patient monitoring and management of diabetes medications.
- Commercial MRs are fortified to prevent micronutrient deficiencies and offer improved palatability.
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