A case of acute stent thrombosis treated successfully with intracoronary tirofiban

Area of Science:

• Cardiology
• Interventional Cardiology
• Pharmacology

Background:

• Acute stent thrombosis (AST) is a rare but serious complication during percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS).
• AST can lead to severe hemodynamic compromise, including cardiogenic shock, with limited treatment options.
• Effective management strategies for AST remain a significant clinical challenge.

Observation:

• A patient with ACS developed cardiogenic shock following percutaneous coronary stent deployment due to acute stent thrombosis.
• Immediate intracoronary administration of tirofiban was performed to address the thrombotic occlusion.
• Coronary blood flow in the target vessel was rapidly restored after tirofiban infusion.

Findings:

• Intracoronary tirofiban effectively reversed the acute stent thrombosis in this ACS patient.
• The prompt restoration of coronary flow led to the reversal of cardiogenic shock.
• This case highlights the potential efficacy of intracoronary tirofiban in managing AST.

Implications:

• Intracoronary tirofiban may represent a valuable therapeutic option for acute stent thrombosis during PCI in ACS.
• This approach could be considered in emergent situations to restore myocardial perfusion and improve patient outcomes.
• Further investigation is warranted to establish the role and safety of intracoronary tirofiban for AST.