Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rheumatic Heart Disease I: Introduction

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

Rheumatic Heart Disease III: Medical Management

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

Rheumatic Heart Disease IV: Nursing Management

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...

Mitral Stenosis III: Medical Management

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...

Endocarditis III: Medical Management

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Difference in Supine versus Standing Plain Radiograph of the Knee in Patients with Knee Osteoarthritis.

Malaysian orthopaedic journal·2025

Same author

On the Identifiability of Genetic Parameters for Growth in Mice With a Massively Deep Pedigree.

Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie·2025

Same author

Influence of systolic blood pressure on outcomes in Nigerians with peripartum cardiomyopathy.

Nigerian journal of clinical practice·2022

Same author

Impact of Parity on Cardiac Structure and Function in Apparently Healthy Pregnant Nigerian Women.

West African journal of medicine·2022

Same author

Correlation between Echocardiographic Left Ventricular Hypertrophy and various Electrocardiographic Criteria of Left Ventricular Hypertrophy among Black Hypertensives.

West African journal of medicine·2021

Same author

TENS for surgical stabilisation of acetabular fracture in the skeletally immature: A novel technique.

Injury·2020

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Published on: November 4, 2021

Multiple embolisations in rheumatic heart disease: a case report.

S A Isezuo¹, A A Musa, S A Saidu

¹Department of Medicine Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. simeonisezuo@yahoo.com

West African Journal of Medicine

|April 29, 2010

Summary

Multiple systemic thromboembolisms, a rare complication of rheumatic valvular disease and atrial fibrillation, can be serious. Continuous anticoagulation is crucial for preventing these embolic events.

More Related Videos

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

Related Experiment Videos

Last Updated: Jun 13, 2026

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Published on: November 4, 2021

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

Area of Science:

Cardiology
Neurology
Vascular Surgery

Background:

Rheumatic valvular disease is a known cause of systemic thromboembolism.
Multiple embolic phenomena are uncommon but serious complications.

Observation:

A 44-year-old patient with rheumatic heart disease and atrial fibrillation presented with multiple embolic events after discontinuing anticoagulation.
Clinical manifestations included chest pain, heart failure, stroke, and limb gangrene.

Findings:

Echocardiography revealed left atrial thrombi and valvular lesions.
CT scan confirmed a cerebral infarct.
Despite initial severe complications, the patient recovered neurologically and remained free of new embolic events with continued anticoagulation.

Implications:

This case highlights the severe risks associated with non-adherence to anticoagulation in valvular atrial fibrillation.
Continuous anticoagulation is essential for preventing recurrent thromboembolic complications in high-risk patients.