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Updated: Jun 13, 2026

Multimodal Cross-Device and Marker-Free Co-Registration of Preclinical Imaging Modalities
Published on: October 27, 2023
A general PDE-framework for registration of contrast enhanced images
Mehran Ebrahimi1, Anne L Martel
1Department of Medical Biophysics, University of Toronto, Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. mehran.ebrahimi@sri.utoronto.ca
Abstract:
This paper presents a general PDE-framework for registration of contrast enhanced images. The approach directly applies the idea of separating the contrast enhancement term from the images in the regularization terms. In our formulation, we stay consistent with existing non-parametric image registration techniques, however, we carry an additional contrast enhancement term throughout. A mathematically rigorous approach is pursued which can exploit various forms of regularization. In this paper, our experiments are built based on diffusion regularization for both contrast enhancement and the deformation field.
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