Related Experiment Video
Updated: Jun 13, 2026

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
Published on: May 24, 2021
Incompressible cardiac motion estimation of the left ventricle using tagged MR images
Xiaofeng Liu1, Khaled Z Abd-Elmoniem, Jerry L Prince
1Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA.
Abstract:
Interpolation from sparse imaging data is typically required to achieve dense, three-dimensional quantification of left ventricular function. Although the heart muscle is known to be incompressible, this fact is ignored by most previous approaches that address this problem. In this paper, we present a method to reconstruct a dense representation of the three-dimensional, incompressible deformation of the left ventricle from tagged MR images acquired in both short-axis and long axis orientations. The approach applies a smoothing, divergence-free, vector spline to interpolate velocity fields at intermediate discrete times such that the collection of velocity fields integrate over time to match the observed displacement components. Through this process, the method yields a dense estimate of a displacement field that matches our observations and also corresponds to an incompressible motion.
