Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Radiation: Applications01:17

Radiation: Applications

The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Looking a Gift Horse in the Mouth: Observations on NHS England's Interim Guidance on Pembrolizumab in Head and Neck Squamous Cell Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2020
Same author

Oropharyngeal Cancers in the East and the West - Implications of Aetiopathogenesis on Prognosis and Research.

Clinical oncology (Royal College of Radiologists (Great Britain))·2019
Same author

Intensity modulated radiotherapy in locally advanced thyroid cancer: Outcomes of a sequential phase I dose-escalation study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2018
Same author

The effect of parotid gland-sparing intensity-modulated radiotherapy on salivary composition, flow rate and xerostomia measures.

Oral diseases·2017
Same author

Normal Tissue Complication Probability (NTCP) Modelling of Severe Acute Mucositis using a Novel Oral Mucosal Surface Organ at Risk.

Clinical oncology (Royal College of Radiologists (Great Britain))·2017
Same author

Standardisation of Target Volume Delineation for Carotid-sparing Intensity-modulated Radiotherapy in Early Glottis Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2016
Same journal

Factors influencing the trustworthiness of non-randomized studies of interventions: a survey of international experts.

BMC medicine·2026
Same journal

Structural-functional network decoupling in early stage amyotrophic lateral sclerosis reveals cell-type specific transcriptional signatures.

BMC medicine·2026
Same journal

A lesion-derived brain network of somatic symptoms for transdiagnostic individual application.

BMC medicine·2026
Same journal

Evaluation and analysis of renal injury in patients with advanced renal cell carcinoma receiving first-line benmelstobart plus anlotinib: results from the ETER100 study.

BMC medicine·2026
Same journal

Adverse and positive childhood experiences and suicidal ideation onset in a US pre-early adolescent cohort.

BMC medicine·2026
Same journal

Dual-drug-loaded nanohydrogel for intraoperative local application: sequential release-mediated spatiotemporal targeting of diverse secondary injury mechanisms to improve long-term prognosis in traumatic brain injury.

BMC medicine·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2026

Radiation Planning Assistant - A Web-based Tool to Support High-quality Radiotherapy in Clinics with Limited Resources
05:18

Radiation Planning Assistant - A Web-based Tool to Support High-quality Radiotherapy in Clinics with Limited Resources

Published on: October 6, 2023

Recent advances in radiotherapy.

S A Bhide1, C M Nutting

  • 1Institute of Cancer Research and Royal Marsden Hospital, Fulham Road, London, UK.

BMC Medicine
|April 30, 2010
PubMed
Summary
This summary is machine-generated.

Radiation therapy has evolved with 3D conformal and intensity modulated radiotherapy (IMRT), sparing normal tissues and enabling dose escalation for cancer treatment. Image-guided radiotherapy (IGRT) is now essential for precise tumor targeting during treatment.

More Related Videos

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Related Experiment Videos

Last Updated: Jun 13, 2026

Radiation Planning Assistant - A Web-based Tool to Support High-quality Radiotherapy in Clinics with Limited Resources
05:18

Radiation Planning Assistant - A Web-based Tool to Support High-quality Radiotherapy in Clinics with Limited Resources

Published on: October 6, 2023

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Area of Science:

  • Radiation Oncology
  • Medical Imaging
  • Cancer Treatment Technologies

Background:

  • Radiation therapy planning has advanced significantly from basic radiographic methods.
  • Technological progress has led to sophisticated techniques like 3D conformal radiotherapy and intensity modulated radiotherapy (IMRT).

Purpose of the Study:

  • To highlight the evolution of radiation therapy techniques.
  • To emphasize the role of IMRT in normal tissue sparing and dose escalation.
  • To underscore the importance of image-guided radiotherapy (IGRT) in modern cancer treatment.

Main Methods:

  • Review of advancements in radiation therapy planning and delivery.
  • Discussion of the principles and benefits of intensity modulated radiotherapy (IMRT).
  • Exploration of the necessity and development of image-guided radiotherapy (IGRT) tools.

Main Results:

  • IMRT allows for precise dose sculpting, sparing healthy tissues and enabling higher radiation doses to tumors.
  • IMRT is a standard for head and prostate cancers and is being explored for other sites.
  • The dynamic nature of tumors during radiation necessitates IGRT for accurate targeting.

Conclusions:

  • IMRT represents a major advancement in radiation oncology, improving therapeutic ratios.
  • Image-guided radiotherapy (IGRT) is crucial for overcoming challenges posed by tumor motion and anatomical variations.
  • Ongoing research focuses on optimizing IGRT hardware and software for enhanced cancer treatment delivery.