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Updated: Jun 13, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
[Diagnosis of abdominal tuberculosis in children]
Xiao-ling Liu1, Shun-ying Zhao
1Special Consultation Internal Medicine, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
Insights
Abdominal tuberculosis in children is often misdiagnosed due to non-specific symptoms. Early recognition requires considering extra-abdominal signs and utilizing PPD tests and ultrasound for diagnosis.
Area of Science:
- Pediatrics
- Infectious Diseases
- Gastroenterology
Context:
- Abdominal tuberculosis (TB) in children presents diagnostic challenges.
- Misdiagnosis is common, often attributed to conditions like gastroenteritis.
Purpose:
- To enhance the recognition and diagnosis of abdominal tuberculosis in pediatric patients.
- To analyze the clinical significance of various diagnostic tests for abdominal TB in children.
Summary:
- Retrospective analysis of 30 pediatric abdominal TB cases revealed high rates of initial misdiagnosis.
- Common symptoms included abdominal pain, distension, and altered bowel habits, with all patients exhibiting positive abdominal signs.
- Extra-abdominal TB was prevalent (24/30), with PPD tests (93%) and ultrasound (100%) showing high positivity. Exploratory laparotomy and colonoscopy provided pathological confirmation.
Impact:
- Highlights the importance of considering abdominal TB in children with gastrointestinal symptoms.
- Emphasizes the utility of PPD testing and ultrasound in early diagnosis.
- Suggests that colonoscopy and laparotomy are valuable for definitive pathological diagnosis.
Objective:
To improve the recognition and diagnosis of abdominal tuberculosis (TB) in children.
Method:
The data from 30 cases with abdominal TB hospitalized in Beijing Children's Hospital were analyzed retrospectively. The clinical significance of various tests was discussed respectively.
Result:
Twenty of the 30 cases were misdiagnosed as having upper respiratory tract infection, gastroenteritis, indigestion, and only 6 cases were diagnosed as pulmonary tuberculosis while the diagnosis of abdominal TB was made in just 4 cases at initial consultation. Twenty-one cases (70%) experienced the symptoms of abdominal pain or distension, diarrhoea, or constipation. The positive abdominal signs existed in all children including doughy sensation (9 cases), tenderness (8 cases), mass (4 cases), and hepatosplenomegaly (3 cases). Extraabdominal TB was found in 24 children, the positive PPD and abnormal ultrasonic image were seen in 93% and 100% of the cases, respectively. The exploratory laparotomy and colonoscopic biopsy confirmed the diagnosis in 3 and 2 cases, respectively. Twenty-four children received systematic treatment with good results.
Conclusion:
The abdominal TB in children which is easily misdiagnosed in it's early stage usually consisted of gastrointestinal symptoms and signs. The TB beyond the abdomen can be a clue for making correct diagnosis. PPD and ventral ultrasonic examination are important for ultimate clinical diagnosis while colonoscopy, and laparotomy can provide pathological evidence.
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