Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Herpes simplex retinitis.

G W Cibis, J T Flynn, E B Davis

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |February 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    A previously healthy infant developed fatal encephalitis and retinitis. Postmortem analysis confirmed herpesvirus infection in the brain and retina, demonstrating its direct infectious nature.

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Soft Foil and Progressive Dentistry.

    International dental journal (Philadelphia, Pa.)·2023
    Same author

    Auscultatory blood pressure measurement: A lost art in pediatric practice.

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2016
    Same author

    Remote image based retinopathy of prematurity diagnosis: a receiver operating characteristic analysis of accuracy.

    The British journal of ophthalmology·2006
    Same author

    Iron supplementation in adolescent hemodialysis patients.

    Clinical nephrology·2005
    Same author

    Episodic gross hematuria in association with allergy symptoms in a child.

    Clinical nephrology·2002
    Same author

    Preschool vision screening using the MTI-Photoscreener.

    Pediatric nursing·2002
    Same journal

    The economics of the initial preventive physical examination in medicare-reply.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    December 2011 archives web quiz winner.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    About this journal.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    In memoriam: goodwin m. Breinin, MD (1918-2011).

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    See all related articles

    Area of Science:

    • Ophthalmology
    • Neurology
    • Virology

    Background:

    • Herpetic retinitis is a severe ocular condition.
    • Encephalitis can occur in infants.

    Observation:

    • An 18-month-old infant presented with fatal encephalitis and retinitis.
    • Clinical signs included whitish-yellow punctate lesions, perivascular cuffing, and hemorrhage.
    • Antibody titers to herpes simplex virus (HSV) significantly increased.

    Findings:

    • Postmortem examination revealed intranuclear inclusion bodies typical of herpesvirus in the brain and retina.
    • Electron microscopy identified herpesvirus particles in the brain and retinal layers.
    • This case confirms the direct infectious nature of herpetic retinitis.

    Implications:

    • Herpes simplex virus can cause severe, direct infection of the retina.
    • Hematogenous spread is a likely route for the virus to reach the retina.
    • This highlights the importance of considering HSV in infant encephalitis and retinitis cases.