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Related Concept Videos

Photoluminescence: Applications01:14

Photoluminescence: Applications

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
Variables Affecting Phosphorescence and Fluorescence01:26

Variables Affecting Phosphorescence and Fluorescence

Fluorescence and phosphorescence are essential phenomena in fields like analytical chemistry, biological imaging, and materials science, where they detect molecular properties and visualize cellular structures. Understanding the variables that influence these luminescent behaviors is crucial for maximizing accuracy and efficiency in their applications. These variables can broadly be grouped into chemical structure, solvent properties, and external conditions, each playing a distinct role in...
Fluorescence and Phosphorescence: Instrumentation01:25

Fluorescence and Phosphorescence: Instrumentation

Fluorometers and spectrofluorometers are two types of instruments used for measuring molecular fluorescence. These instruments differ in how they select excitation and emission wavelengths and the type of light sources they utilize. Fluorometers use absorption interference filters to choose excitation and emission wavelengths. The excitation source in a fluorometer is typically a low-pressure mercury vapor lamp that emits intense lines distributed throughout the ultraviolet and visible regions.
Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the para position.

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High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
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Published on: January 27, 2013

Fluorescent chemosensors for Zn(2+).

Zhaochao Xu1, Juyoung Yoon, David R Spring

  • 1Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.

Chemical Society Reviews
|April 30, 2010
PubMed
Summary

Fluorescent chemosensors for zinc ions (Zn2+) are crucial for biological studies due to their sensitivity. This review classifies these sensors by their receptor units, the core component.

Area of Science:

  • Analytical Chemistry
  • Biochemistry
  • Chemical Sensing

Background:

  • Zinc ions (Zn2+) play vital roles in biological systems.
  • Fluorescence assays offer high sensitivity and simplicity for detecting Zn2+.
  • Fluorescent chemosensors for Zn2+ have gained significant research interest.

Purpose of the Study:

  • To provide a tutorial review on fluorescent chemosensors for zinc ions.
  • To classify zinc chemosensors based on their receptor unit types.
  • To highlight the importance of the receptor as the central processing unit.

Main Methods:

  • Classification of chemosensors based on receptor design.
  • Review of existing literature on fluorescent zinc chemosensors.
  • Analysis of the structure-function relationship of receptor units.

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Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology

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Last Updated: Jun 13, 2026

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10:07

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels

Published on: January 27, 2013

Characterizing Mammalian Zinc Transporters Using an In Vitro Zinc Transport Assay
07:55

Characterizing Mammalian Zinc Transporters Using an In Vitro Zinc Transport Assay

Published on: June 2, 2023

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Main Results:

  • Chemosensors are composed of fluorophore, spacer, and receptor units.
  • The receptor unit is identified as the critical component for Zn2+ recognition.
  • A classification system based on receptor types is presented.

Conclusions:

  • Understanding receptor types is key to designing effective Zn2+ chemosensors.
  • This classification aids in the development of novel and improved fluorescent sensors for biological applications.
  • Fluorescent chemosensors remain a powerful tool for studying Zn2+ in biological contexts.