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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
[Proposed preoperative risk score for patients candidate to cardiac valve surgery]
João Carlos Vieira da Costa Guaragna1, Luiz Carlos Bodanese, Fabiana Lucas Bueno
1Hospital São Lucas, Pontificia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil. guaragna@cardiol.br
Insights
A new risk score identifies key factors for in-hospital death after heart valve surgery. This tool helps stratify patients into risk categories for better preoperative assessment and care.
Area of Science:
- Cardiovascular Surgery
- Medical Risk Stratification
- Health Outcomes Research
Context:
- Assessing preoperative risk is crucial for patient counseling and intraoperative management in cardiac surgery.
- Cardiac valve surgery carries significant risks, necessitating accurate mortality prediction.
- Existing risk models may require refinement for specific patient populations.
Purpose:
- To identify preoperative risk factors associated with in-hospital mortality in patients undergoing cardiac valve surgery.
- To develop and validate a simple, practical risk score for predicting in-hospital mortality.
- To aid clinicians at Hospital São Lucas of Pontifícia Universidade Católica do Rio Grande do Sul (HSL-PUCRS) in patient risk assessment.
Summary:
- A study of 1,086 adult patients undergoing cardiac valve surgery identified nine independent predictors of in-hospital mortality.
- These predictors include advanced age, surgical priority, female sex, low ejection fraction, concomitant coronary artery bypass grafting (CABG), pulmonary hypertension, advanced NYHA functional class, and elevated creatinine levels.
- A validated risk score was developed, demonstrating good predictive capacity (Area Under the ROC Curve = 0.83) and classifying patients into five risk categories.
Impact:
- The developed risk score offers a simplified tool for daily clinical practice to assess preoperative risk in cardiac valve surgery patients.
- Facilitates informed patient discussions regarding surgical risks and expected outcomes.
- Enables tailored perioperative care strategies based on identified risk levels.
Background:
To establish a risk score for heart surgery allows the assessment of preoperative risk, informing the patient and defining care during the intervention.
Objective:
To assess preoperative risk factors for death in cardiac valve surgery and construct a simple risk model (score) for in-hospital mortality of patients candidate to surgery at Hospital São Lucas of Pontifícia Universidade Católica do Rio Grande do Sul (HSL-PUCRS).
Methods:
The study sample included 1,086 adult patients that underwent cardiac valve surgery between January 1996 and December 2007 at HSL-PUCRS. Logistic regression was used to identify risk and in-hospital mortality factors. The model was developed in 699 patients and its performance was tested in the remaining data (n = 387). The final model was created using the total study sample (n = 1,086).
Results:
Global mortality was 11.8%: 8.8% of elective cases and 63.8% of emergency cases. At the multivariate analysis, 9 variables remained independent predictors for the outcome: advanced age, surgical priority, female sex, ejection fraction < 45%, concomitant myocardial revascularization (CABG), pulmonary hypertension, NYHA functional class III or IV, creatinine levels (1.5 to 2.49 mg/dl and > 2.5 mg/dl or undergoing dialysis). The area under the ROC curve was 0.83 (95% CI: 0.78-0.86). The risk model showed good capacity for observed/predicted mortality: the Hosmer-Lemeshow test was x(2) = 5.61; p = 0.691 and r = 0.98 (Pearson's coefficient).
Conclusion:
The variables predictive of in-hospital mortality allowed the construction of a simplified risk score for daily practice, which classifies the patient as having low, moderate, high, very high and extremely high preoperative risk.
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