Related Experiment Video
Updated: Jun 13, 2026

Optimized Interferon-gamma ELISpot Assay to Measure T Cell Responses in the Guinea Pig Model after Vaccination
Published on: January 20, 2019
[Evolution of the immunization coverage of 13 to 14 year-old adolescents in Geneva between four years]
Emilien Jeannot1, Claire-Anne Wyler, Olivier Duperrex
1Institut de médecine sociale et préventive, Faculté de Médecine, Université de Genève, Suisse, Centre Medical Universitaire, avenue Michel Servet 1, 1211 Genève 4, Suisse.
Abstract:
This study aims to examine changes in immunization coverage for diphtheria, tetanus, whooping cough, polio, measles, mumps, rubella and hepatitis B during the academic calendars of 2003-2004 and 2007-2008 for students aged 13 to 14 years. Data were collected on an annual basis and systematically from the vaccination records 85% of adolescents enrolled in public institutions in Geneva. The immunization coverage increased for diphtheria, tetanus and polio by 2.3, 2.1 and 1.1 points respectively. Vaccination for pertussis (whooping cough) increased from 20.7% in 2003-2004 to 61% in 2007-2008. Vaccinations administered against measles, mumps and rubella increased by nearly 20 points. During this period, the coverage rate for hepatitis B increased by 10.3 points in 5 years. The recommended vaccination coverage rates are not being achieved for any of the vaccines currently being used in Switzerland, with the exception of those for diphtheria and polio.
Related Concept Videos
Vaccinations
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Vaccines
Microorganisms in Medicine and Therapeutics
Smallpox
Gene Therapy
