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Related Experiment Video

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Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad
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Published on: January 20, 2019

Breast plasmacytoma.

Alexey Surov1, Hans-Jürgen Holzhausen, Katrin Ruschke

  • 1Department of Radiology, Martin-Luther-University of Halle-Wittenberg, Halle, Germany. alex.surow@medizin.uni-halle.de

Acta Radiologica (Stockholm, Sweden : 1987)
|May 1, 2010
PubMed
Summary
This summary is machine-generated.

Breast plasmacytoma (BP) is rare and often presents as a breast lump. Due to non-specific features, it can be misdiagnosed, highlighting the need for consideration in multiple myeloma patients.

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Non-enzymatic, Serum-free Tissue Culture of Pre-invasive Breast Lesions for Spontaneous Generation of Mammospheres

Published on: November 8, 2014

Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Breast plasmacytoma (BP) is an exceptionally rare condition, with limited statistical data available, primarily from case reports.
  • Understanding its clinical and radiological characteristics is crucial for accurate diagnosis.

Purpose of the Study:

  • To delineate the clinical signs and radiological features of breast plasmacytoma.
  • To improve diagnostic accuracy and differentiate BP from other breast pathologies.

Main Methods:

  • A retrospective analysis of five BP cases from institutional databases (1997-2009).
  • A comprehensive literature review collecting 48 additional cases (1988-present).
  • Total study cohort comprised 53 patients with breast plasmacytoma.

Main Results:

  • BP occurred as primary in 15% and secondary to multiple myeloma (MM) in 85% of cases.
  • Common presentations included breast lumps (83%) and mammographic masses (89%).
  • Radiological findings were often non-specific, mimicking breast carcinoma or benign lesions.

Conclusions:

  • Breast plasmacytoma lacks specific clinical and radiological indicators, increasing the risk of misdiagnosis.
  • BP must be included in the differential diagnosis of breast lesions, particularly in patients with a history of multiple myeloma.