The biomass objective function
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Updated: Jun 13, 2026

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
Published on: December 4, 2021
Adam M Feist1, Bernhard O Palsson
1GT Life Sciences, Inc., 10520 Wateridge Circle, San Diego, CA 92122, USA.
Abstract:
Flux balance analysis (FBA) is a mathematical approach for analyzing the flow of metabolites through a metabolic network. To computationally predict cell growth using FBA, one has to determine the biomass objective function that describes the rate at which all of the biomass precursors are made in the correct proportions. Here we review fundamental issues associated with its formulation and use to compute optimal growth states.
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