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Related Experiment Video

Updated: Jun 13, 2026

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
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Ortner syndrome in infants.

Syed Ahmed Zaki1, Shujaath Asif, Preeti Shanbag

  • 1Department of Pediatrics, Lokmanya Tilak Municipal General Hospital, Sion, Mumbai, Maharashtra, India. drzakisyed@gmail.com

Indian Pediatrics
|May 1, 2010
PubMed
Summary

Ortner syndrome, or cardiovocal syndrome, causes hoarseness in infants due to heart conditions compressing the recurrent laryngeal nerve. This study links dilated pulmonary arteries in congenital heart disease to this nerve paralysis and voice changes.

Area of Science:

  • Pediatric Cardiology
  • Neurology
  • Otolaryngology

Background:

  • Ortner syndrome, also known as cardiovocal syndrome, describes hoarseness resulting from recurrent laryngeal nerve paralysis caused by cardiovascular disease.
  • Congenital heart disease (CHD) can lead to cardiovascular abnormalities that may affect cranial nerves.

Observation:

  • This report details three infant cases of Ortner syndrome associated with congenital heart disease.
  • All infants presented with moderate to severe pulmonary hypertension and a moderately dilated pulmonary artery.

Findings:

  • The dilated pulmonary artery in these cases is hypothesized to compress the left recurrent laryngeal nerve.
  • This compression is believed to be the direct cause of the observed hoarseness in the infants.

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Implications:

  • This highlights a potential, previously underrecognized cause of hoarseness in infants with specific congenital heart defects.
  • Early recognition of cardiovocal syndrome in infants with CHD and pulmonary hypertension is crucial for timely diagnosis and management.
  • Further research is warranted to elucidate the precise mechanisms and prevalence of Ortner syndrome in pediatric populations with cardiovascular conditions.