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Updated: Jun 13, 2026
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Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Endoscopic mucosal resection: early experience in British Columbia
Mayur Brahmania1, Eric Lam, Jennifer Telford
1Department of Medicine, Division of Gastroenterology, St Paul's Hospital, University of British Columbia, Vancouver, British Columbia.
Summary
Endoscopic mucosal resection (EMR) effectively treats esophageal dysplasia and early cancers. Most patients achieved remission, though strictures may require additional interventions.
Area of Science:
- Gastroenterology
- Endoscopy
- Oncology
Background:
- Endoscopic mucosal resection (EMR) is a proposed primary treatment for esophageal dysplasia and mucosal cancers.
- Barrett's esophagus is a precancerous condition requiring effective management strategies.
Purpose of the Study:
- To assess the efficacy and safety of EMR for Barrett's esophagus with dysplasia or early adenocarcinoma.
- Evaluate complication rates and long-term outcomes of EMR in this patient population.
Main Methods:
- Retrospective review of patients undergoing EMR at St Paul's Hospital.
- Inclusion criteria: aggressive biopsy protocols, staging via endoscopic ultrasound and CT, and follow-up >1 year.
- EMR performed using a commercial device, repeated until complete resection.
Main Results:
- Twenty-two male patients (mean age 67) with Barrett's esophagus (mean length 5.5 cm) were treated.
- Diagnoses included high-grade dysplasia (15 patients) and adenocarcinoma (3 patients).
- 82% of patients (18/22) showed no evidence of dysplasia or cancer at 2-year median follow-up; 3 strictures occurred, managed conservatively or with dilation.
Conclusions:
- EMR is a viable treatment for most patients with esophageal dysplasia and early adenocarcinoma.
- Pre-existing strictures may necessitate alternative endoscopic or surgical approaches.
- EMR offers a high success rate for managing Barrett's esophagus complications.
