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Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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Published on: December 9, 2015

(p)ppGpp and drug resistance.

Jun Wu1, Quanxin Long, Jianping Xie

  • 1Institute of Modern Biopharmaceuticals, School of Life Sciences, Southwest University, Chongqing, China.

Journal of Cellular Physiology
|May 1, 2010
PubMed
Summary

The rise of antibiotic-resistant bacteria necessitates new drugs. Alarmones like guanosine tetraphosphate and pentaphosphate ((p)ppGpp) contribute to resistance, but analogs show promise as novel antibiotics.

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