Related Experiment Video
Updated: Jun 13, 2026

10:02
State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Giant dural venous sinus ectasia in neonates
Benoit Jenny1, Michel Zerah, Dale Swift
1University Hospital Geneva, Switzerland.
Journal of Neurosurgery. Pediatrics
|May 4, 2010
Summary
Posterior giant dural venous sinus ectasia in neonates can spontaneously thrombose and regress, leading to favorable outcomes in some cases. This condition, diagnosed antenatally, may not require surgical intervention beyond supportive care.
Area of Science:
- Neurology
- Pediatrics
- Radiology
Background:
- Posterior giant dural venous sinus ectasia is a rare condition diagnosed antenatally.
- This report details four recent cases in neonates across three institutions.
Observation:
- Diagnosis was confirmed using antenatal ultrasonography, prenatal MR imaging, and postnatal MR angiography.
- Affected neonates presented with cardiac insufficiency and signs of increased intracranial pressure post-birth.
- Surgical interventions for increased intracranial pressure provided no significant benefit.
Findings:
- No obvious arteriovenous malformations were detected, though secondary arteriovenous fistulas are hypothesized.
- Spontaneous, progressive thrombosis and regression of the venous sinus ectasia were observed in all cases.
- Histopathology revealed stratified thrombi of varying ages within the dura mater.
Implications:
- Progressive thrombosis appears to be the natural evolution of this condition.
- Favorable clinical outcomes were observed in some cases without specific surgical treatment, highlighting the role of supportive care.
- Understanding the natural history of venous sinus ectasia is crucial for appropriate management strategies.
Related Concept Videos
Veins of Head and Neck
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Overview of Systemic Veins
Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Anatomy of the Brain: Ventricles
There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen. The...