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Angiitis of the central nervous system
1Mayo Clinic, Rochester, Minnesota.
Current Opinion in Rheumatology
|February 1, 1991
Summary
Central nervous system angiitis involves blood vessel inflammation, potentially causing organ damage. This review examines primary, spinal cord, and secondary central nervous system angiitis, detailing associated underlying disorders.
Area of Science:
- Neurology
- Immunology
- Vascular Medicine
Background:
- Angiitis, or blood vessel inflammation, can affect the central nervous system (CNS).
- CNS vasculitides are often associated with underlying systemic or autoimmune disorders.
- This inflammation can lead to vessel wall damage, occlusion, and ischemic injury to CNS organs.
Purpose of the Study:
- To review primary granulomatous angiitis of the CNS.
- To discuss spinal cord angiitis.
- To cover secondary CNS angiitis and its related underlying disorders.
Main Methods:
- Literature review of primary and secondary CNS angiitis.
- Analysis of underlying disorders associated with CNS vasculitides.
- Synthesis of information on granulomatous angiitis affecting the CNS and spinal cord.
Main Results:
- Primary granulomatous angiitis of the CNS is a distinct entity.
- Spinal cord involvement in angiitis is significant.
- Secondary CNS angiitis is frequently linked to specific systemic conditions.
Conclusions:
- Understanding the diverse causes of CNS angiitis is crucial for diagnosis and management.
- Identifying underlying disorders is key to treating secondary CNS vasculitis.
- This review provides a comprehensive overview of CNS angiitis and its associations.