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Updated: Jun 13, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

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Published on: July 13, 2019

Infectious and thrombotic complications of central venous catheters

Nadine Nakazawa1

  • 1Stanford Hospital & Clinics, Stanford, CA, USA. nnakazawa17@hotmail.com

Seminars in Oncology Nursing
|May 4, 2010
PubMed

Insights

Preventing and managing infectious and thrombotic complications of central venous access devices (CVADs) is crucial for patient safety. Understanding pathogenesis and adhering to best practices minimize risks associated with these common CVAD complications.

Area of Science:

  • Medical Science
  • Infectious Diseases
  • Vascular Access

Background:

  • Central venous access devices (CVADs) are essential in modern healthcare but are associated with significant infectious and thrombotic complications.
  • These complications can lead to severe patient morbidity, increased healthcare costs, and prolonged hospital stays.
  • Patient safety initiatives increasingly focus on preventing catheter-related bloodstream infections.

Purpose of the Study:

  • To comprehensively review the pathogenesis, prevention, and management strategies for infectious and thrombotic complications of CVADs.
  • To highlight the critical role of healthcare professionals in mitigating these risks.
  • To emphasize the importance of consistent adherence to best practices in CVAD care.

Main Methods:

  • Literature review encompassing journal articles and case reports.
  • Inclusion of product information and professional guidelines.
  • Incorporation of personal clinical experience.

Main Results:

  • Infectious and thrombotic complications are frequent and serious adverse events associated with CVADs.
  • Effective prevention and management strategies are essential to improve patient outcomes.
  • National focus on patient safety underscores the need for robust infection control measures.

Conclusions:

  • Clinicians play a pivotal role in the prevention and identification of CVAD-related complications.
  • A thorough understanding of the pathogenesis of these complications is fundamental for effective management.
  • Consistent application of best practices across all clinical settings is critical to minimize patient risk.
Abstract

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