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Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Severe manifestation of oral pemphigus
Etiene de Andrade Munhoz1, Camila Lopes Cardoso, Jaison Antônio Barreto
1Department of Stomatology, Bauru School of Dentistry, University of São Paulo, Al. Dr Otávio Pinheiro Brisolla 9-75, Bauru, SP, Brazil.
Abstract:
This article describes a case of pemphigus vulgaris in a relatively young patient with exacerbated characteristics, widespread lesions, and rapid evolution. A 40-year-old woman sought treatment, complaining about severe oral pain and dysphagia. Intraoral inspection revealed ulcerated lesions on the lips, buccal mucosa, and floor of the mouth. The number of lesions quickly increased and resembled erythema multiforme. She also presented blistering lesions on the back, abdomen, neck, and eyes. Incisional oral biopsy revealed pemphigus vulgaris. This report emphasizes the importance of early diagnosis of an oral biopsy in systemic diseases and the management of the lesions.
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