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Updated: Jun 13, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Perioperative management of the patient with cardiac disease
Robert C Decker1, Jennifer R Foley, Thomas J Moore
1Department of Orthopaedic Surgery, Emory University, Atlanta, GA, USA.
Insights
Patients with coronary artery disease face higher risks during surgery. Preoperative cardiac testing and specific postoperative management strategies can reduce perioperative cardiac complications in orthopaedic patients.
Area of Science:
- Cardiology
- Orthopaedic Surgery
- Anesthesiology
Background:
- Perioperative death incidence is low, but coronary artery disease increases cardiac complication risk.
- Orthopaedic surgery patients with known cardiac disease require careful perioperative management.
- Emergent orthopaedic procedures pose a higher risk of perioperative cardiac events compared to elective ones.
Purpose of the Study:
- To review current recommendations for preoperative cardiac testing in orthopaedic patients.
- To outline perioperative management strategies for orthopaedic patients with known cardiac disease.
- To reduce postoperative mortality and morbidity in at-risk surgical populations.
Main Methods:
- Review of current clinical guidelines and evidence-based practices.
- Analysis of risk factors for perioperative cardiac events in orthopaedic surgery.
- Discussion of pharmacological interventions (beta blockers, statins, alpha-2 agonists) for cardiac protection.
Main Results:
- Preoperative cardiac testing is indicated for select orthopaedic patients to identify and mitigate risks.
- Continuation or initiation of specific medications (beta blockers, statins, alpha-2 agonists) postoperatively can improve cardiac outcomes.
- Risk stratification is crucial for tailoring management strategies.
Conclusions:
- Judicious preoperative cardiac evaluation is essential for orthopaedic patients.
- Optimized perioperative management, including targeted medical therapies, is key to improving outcomes.
- Reducing perioperative cardiac complications is achievable through evidence-based testing and management.
Abstract:
The overall incidence of perioperative death is relatively low. However, patients with coronary artery disease are at higher than average risk of perioperative cardiac complications. Thus, preoperative testing for cardiac disease should be done in certain patients in an effort to reduce postoperative mortality and morbidity. Patients who require emergent orthopaedic surgery are at greater risk of perioperative cardiac events than are those who undergo elective procedures. Certain modalities, such as beta blockers, statins, and alpha-2 agonists, may be started or continued in the postoperative period to further enhance cardiac function. We review the current recommendations for preoperative cardiac testing in orthopaedic patients and for perioperative management of orthopaedic patients with known cardiac disease.
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