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Related Concept Videos

Randomized Experiments01:13

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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Related Experiment Video

Updated: Jun 13, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

Supported employment: randomised controlled trial.

Louise M Howard1, Margaret Heslin, Morven Leese

  • 1Health Service and Population Research Department, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK.

The British Journal of Psychiatry : the Journal of Mental Science
|May 4, 2010
PubMed
Summary
This summary is machine-generated.

Individual Placement and Support (IPS) did not significantly improve competitive employment for individuals with severe mental illness in South London. Implementation challenges in the UK context may explain these findings.

Related Experiment Videos

Last Updated: Jun 13, 2026

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers
08:33

A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging Biomarkers

Published on: January 5, 2024

Area of Science:

  • Psychiatry
  • Vocational Rehabilitation
  • Health Services Research

Background:

  • Individual Placement and Support (IPS) is an evidence-based model for supported employment.
  • North American trials show IPS effectiveness for individuals with severe mental illness.
  • Limited international trials exist, particularly in the UK.

Purpose of the Study:

  • To evaluate the effectiveness and cost-effectiveness of IPS in the UK.
  • To assess IPS impact on competitive employment for individuals with severe mental illness.

Main Methods:

  • Randomized controlled trial in South London.
  • Participants with severe mental illness allocated to IPS or traditional vocational services (treatment as usual).
  • Follow-up assessment at 1 year.

Main Results:

  • No significant difference in competitive employment rates between IPS and treatment as usual groups (13% vs 7%).
  • Risk ratio for obtaining employment was 1.35 (95% CI 0.95-1.93, P=0.15).
  • No significant differences observed in secondary outcomes.

Conclusions:

  • IPS did not demonstrate significant benefit for competitive employment in this South London cohort at 1-year follow-up.
  • Suboptimal implementation and structural challenges in the UK context may have impacted results.
  • Lack of integration with mental health services and economic disincentives could affect motivation for both patients and professionals.