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Updated: Jun 13, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
Genetics and genomics of endometriosis
Keith A Hansen1, Kathleen M Eyster
1Department of Obstetrics and Gynecology, Sanford School of Medicine of University of South Dakota, Vermillion and Sioux Falls, South Dakota 57107, USA. kahansen@usd.edu
Abstract:
Endometriosis is a common cause of morbidity in women with an unknown etiology. Studies have demonstrated the familial nature of endometriosis and suggest that inheritance occurs in a polygenic/multifactorial fashion. Studies have attempted to define the gene or genes responsible for endometriosis through association or linkage studies with candidate genes or DNA mapping technology. A number of genomics studies have demonstrated significant alterations in gene expression in endometriosis. A more thorough understanding of the genetics and genomics of endometriosis will facilitate understanding the basic biology of the disease and open new inroads to diagnosis and treatment of this enigmatic condition.
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