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Published on: February 22, 2019
[Pertussis keeps on killing]
Joana Freitas1, Susana Gama de Sousa, Cristina Miguel
1Serviço de Pediatria, CHMA, EPE - Unidade de Famalicão.
Insights
Pertussis (whooping cough) is a dangerous bacterial infection. Early recognition and new vaccination strategies are crucial to protect vulnerable infants from this potentially fatal disease, as pertussis is not expected to be eradicated soon.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Pertussis, caused by Bordetella pertussis, is a highly infectious global respiratory illness.
- Recent years show an increase in pertussis cases, with adolescents and adults emerging as significant infection sources for infants.
Observation:
- A 36-day-old infant presented with respiratory distress and cyanosing cough, suspected pertussis complicated by pneumonia.
- Initial treatment with broad-spectrum antibiotics was initiated, but the infant's condition worsened.
Findings:
- The infant developed hyperleukocytosis and thrombocytosis, was transferred to the ICU, and died within 20 hours due to pulmonary hypertension and hemorrhage.
- Pertussis infection was confirmed via PCR.
Implications:
- The case highlights the critical need for recognizing pertussis, even in atypical presentations, for timely diagnosis and treatment.
- Emphasizes the importance of reporting, disease prevention, and developing new vaccination strategies to protect vulnerable populations, particularly unvaccinated infants.
Abstract:
Pertussis, or whooping cough, is a highly infectious respiratory disease, endemic all over the world, caused by bacteria Bordetella pertussis. The authors describe the case of a 36 day old infant, brought to the emergency room due to respiratory distress and cyanosing cough, admitted with suspected pertussis infection complicated by bacterial pneumonia, having begun large spectrum antibiotics. Labs showed hyperleukocytosis and thrombocytosis. She was transferred to an Intensive Care Unit because of a worsened state, dying 20 hours after admission with pulmonary hypertension and haemorrhage. Pertussis was diagnosed by PCR. Over the last few years, there has been an increase in the number of cases of pertussis. Adolescents and adults have become an under-recognized but significant source of infection, particularly to small unvaccinated infants. The authors underline the importance of recognizing pertussis, so that even in its atypical presentation, one can suspect, treat, report and prevent a disease that is not, and is not expected to be, eradicated any time soon. New vaccination strategies are necessary, to avoid this disease, which can be fatal to the most vulnerable.
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