Combined Kerarings and Artisan/Artiflex IOLs in Keratectasia

PURPOSE:To evaluate the results of combined intracorneal ring (Keraring, Mediphacos Ltd) and anterior chamber, iris-fixated, phakic intraocular lens (pIOL) (Artisan and Artiflex, Ophtec BV) implantation in patients with ectatic corneal conditions and secondary high myopic and astigmatic refractive error. METHODS:Ten eyes of eight consecutive patients with different ectatic corneal diseases underwent sequential intracorneal Keraring and iris-fixated pIOL implantation. Two eyes with keratoconus, one eye with pellucid marginal degeneration, and one eye with iatrogenic corneal ectasia were implanted with the Artisan pIOL; six eyes with keratoconus were implanted with the Artiflex pIOL. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent (MRSE), topographic findings, and complications were recorded. RESULTS:Mean UDVA improved from 0.02+/-0.10 pre-operatively to 0.11+/-0.06 after Keraring implantation and to 0.54+/-0.18 after pIOL implantation (P<.001 for all). Mean CDVA improved from 0.18+/-0.12 preoperatively to 0.39+/-0.13 after Keraring implantation and to 0.66+/-0.18 after pIOL implantation (P<.001 for all). Mean MRSE reduced from -12.50+/-6.31 D preoperatively to +/-12.08+/-5.17 D after Keraring implantation (P=.10) and to -0.10+/-0.84 D after pIOL implantation (P<.001). No intra- or postoperative complications were observed. CONCLUSIONS:Sequential intracorneal Keraring segments and Artisan/Artiflex pIOL implantation resulted in visual and refractive improvements in patients with different corneal ectatic conditions with high myopic refractive errors.