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Control of pancreatic secretion in humans

J Morisset1

  • 1Service de gastroentérologie, Département de médecine, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, Québec, Canada. jean.morisset@usherbrooke.ca

Advances in Medical Sciences
|May 5, 2010
PubMed

Insights

This review summarizes human pancreatic secretion control, covering development in newborns, meal responses, dietary effects, and underlying mechanisms and receptors.

Area of Science:

  • Gastroenterology
  • Physiology
  • Pediatrics

Background:

  • Studying human pancreatic secretion control is challenging due to patient availability and ethical considerations.
  • Despite difficulties, research has provided insights into pancreatic function across different age groups.

Purpose of the Study:

  • To review the development of pancreatic secretory processes in newborns.
  • To outline pancreatic responses to meals, dietary components, and involved control mechanisms and receptors.

Main Methods:

  • Literature review of existing studies on human pancreatic secretion.
  • Synthesis of data on developmental, meal-induced, and dietary-related pancreatic responses.

Main Results:

  • Knowledge gaps exist regarding pancreatic secretion control, particularly in newborns.
  • Pancreatic responses vary based on meal composition and are regulated by complex mechanisms.

Conclusions:

  • Further research is needed to fully elucidate pancreatic secretion control, especially in early life.
  • Understanding these controls is crucial for managing gastrointestinal and nutritional health.

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