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Updated: Jun 13, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death
Published on: August 2, 2019
How the distinction between "irreversible" and "permanent" illuminates circulatory-respiratory death determination
1Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA. bernat@dartmouth.edu
Physicians determine death by permanent cessation of circulation and respiration, which indicates irreversible cessation. This ensures organ donation after circulatory death (DCD) protocols align with legal statutes and the dead donor rule.
Area of Science:
- Medical Ethics
- Organ Donation
- Forensic Medicine
Background:
- Understanding the precise definition of death is crucial for medical and legal practices.
- Distinguishing between permanent and irreversible cessation of functions is key for death determination.
Purpose of the Study:
- To clarify the distinction between permanent and irreversible cessation of circulatory and respiratory functions.
- To affirm the validity of death determinations in donation after circulatory death (DCD) protocols.
Main Methods:
- Analysis of the medical and legal definitions of death.
- Examination of the criteria used in circulatory-respiratory tests for death determination.
- Review of the implications for organ donation protocols.
Main Results:
- Permanent cessation of circulation and respiration is the accepted medical standard for determining death.
- Permanent cessation serves as a reliable indicator of irreversible cessation.
- This standard allows for more timely declarations of death.
Conclusions:
- Patients declared dead under donation after circulatory death (DCD) protocols meet statutory requirements.
- The medical standard of permanent cessation does not violate the dead donor rule.
- Clarifying DCD as 'donation after circulatory death' emphasizes the correct death standard.
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