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Transcranial Direct Current Stimulation for Online Gamers

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Frontotemporal dementia presenting as pathological gambling.

Facundo F Manes¹, Teresa Torralva, María Roca

¹Institute of Cognitive Neurology (INECO), Favaloro University, Castex 3293 (1425), Buenos Aires, Argentina. fmanes@neurologiacognitiva.org

Nature Reviews. Neurology

|May 5, 2010

Summary

This summary is machine-generated.

This case study highlights behavioral variant frontotemporal dementia (bvFTD) presenting with pathological gambling and personality changes. Neuropsychological testing and imaging confirmed bvFTD, leading to targeted treatment and family support.

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Area of Science:

Neuroscience
Neurology
Behavioral Neurology

Background:

A 69-year-old woman exhibited pathological gambling, disinhibition, empathy loss, and ritualistic behaviors.
Initial assessments revealed selective impairment on the Iowa Gambling Task, mimicking behavioral variant frontotemporal dementia (bvFTD).

Observation:

Standard neuropsychological tests were normal, but the Iowa Gambling Task showed deficits.
Magnetic Resonance Imaging (MRI) indicated frontal lobe atrophy.
Hexamethylpropyleneamine oxime single-photon emission computed tomography (HMPAO-SPECT) corroborated the MRI findings.

Findings:

The patient was diagnosed with behavioral variant frontotemporal dementia (bvFTD).
Pharmacological treatment included paroxetine for impulsivity and carbamazepine for mood stabilization.
Family counseling addressed behavioral and legal concerns.

Implications:

This case underscores the importance of specialized neuropsychological assessments in diagnosing bvFTD.
Early diagnosis and intervention, including pharmacological and supportive therapies, are crucial for managing bvFTD symptoms.
Understanding the neurobiological underpinnings of bvFTD can inform future treatment strategies and patient care.