Fulminant pulmonary aspergillus infection occluding the aortic arch after high-dose antileukemic chemotherapy

After antileukemic chemotherapy a granulocytopenic patient experienced a rapidly progressive left-sided pneumonia with pleuritic pain. After 1 week, a sudden occlusion of all aortic branches was followed by death. At postmortem, a huge thrombus in the aortic arch caused by Aspergillus invasion from the left lung was found.