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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

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Related Experiment Video

Updated: Jun 13, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Young man with asthma and infertility.

F J Gonzalez Barcala1, A Pena, L Herrero

  • 1Servicio de Neumologia, Hospital de Pontevedra, Pontevedra, Spain. fjgbarcala@telefonica.net

Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace
|May 6, 2010
PubMed
Summary

Alpha-1 antitrypsin (AAT) deficiency, a condition causing lung and liver issues, may also link asthma and male infertility. Testing for AAT deficiency is recommended for males with both conditions.

Related Experiment Videos

Last Updated: Jun 13, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

  • Pulmonology
  • Andrology
  • Genetics

Background:

  • Asthma and male infertility are prevalent conditions.
  • These conditions can share common pathophysiological mechanisms.
  • Co-occurrence in the same patient necessitates investigation into shared underlying causes.

Observation:

  • A patient presented with persistent asthma symptoms including cough and wheezing.
  • The patient had a documented history of infertility spanning five years.
  • Asthma diagnosis was confirmed and treatment yielded positive results.

Findings:

  • Alpha-1 antitrypsin (AAT) levels were investigated due to the patient's dual diagnosis.
  • The patient was diagnosed with phenotype SZ AAT deficiency.
  • This finding aligns with recent evidence suggesting a link between AAT deficiency, asthma, and male infertility.

Implications:

  • AAT deficiency should be considered in the differential diagnosis for males presenting with both asthma and infertility.
  • Further research is warranted to elucidate the specific pathophysiological links.
  • Screening for AAT deficiency may improve diagnostic and therapeutic strategies for affected individuals.