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Updated: Jun 13, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

Published on: November 1, 2015

Systemic lupus erythematosus and its ABCs (APRIL/BLyS complexes)

William Stohl

    Arthritis Research & Therapy
    |May 6, 2010
    PubMed
    Summary

    BLyS and APRIL, related TNF ligands, form unique heterotrimers. These complexes are elevated in systemic lupus erythematosus (SLE) patients, suggesting a potential role in SLE pathogenesis.

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