Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac conduction defects associated with hyponatremia.

M Mouallem1, E Friedman, Y Shemesh

  • 1Department of Internal Medicine E, Chaim Sheba Medical Center, Tel Hashomer, Israel.

Clinical Cardiology
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The power of physicians: autonomy and balance in a changing system.

The American journal of medicine·1995
Same author

Constitutional and somatic mutations in the WT1 gene in Wilms' tumor patients.

International journal of cancer·1995
Same author

Platelet-derived growth factor-B increases colon cancer cell growth in vivo by a paracrine effect.

Journal of cellular physiology·1995
Same author

Analysis of microsatellite repeats in pediatric brain tumors.

Cancer genetics and cytogenetics·1995
Same author

Dopamine receptor stimulation decreases cytosolic gamma protein kinase C immunoreactivity in rat hippocampal slices: evidence for increased Ca(2+)-dependent proteolysis.

Journal of neurochemistry·1995
Same author

Colon carcinoma cells with inactive nm23 show increased motility and response to motility factors.

Carcinogenesis·1995

Severe hyponatremia may contribute to cardiac conduction defects, such as atrioventricular (AV) block, particularly in patients with pre-existing heart conditions. This study highlights a potential link between low sodium levels and heart rhythm disturbances.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Endocrinology

Background:

  • Cardiac conduction defects are common, but their association with hyponatremia is not well-established.
  • Ventricular premature beats in heart failure patients correlate with hyponatremia severity.

Observation:

  • Three patients presented with second-degree or complete atrioventricular (AV) block during or after severe hyponatremia.
  • Causes included thiazide-induced hyponatremia with amiodarone, idiopathic hyponatremia with polydipsia, and diuretic-induced hyponatremia in ischemic heart disease.

Findings:

  • Hyponatremia coincided with AV block in all three cases.
  • The third patient showed intermittent conversion of first-degree to second-degree AV block during hyponatremia.

Related Experiment Videos

Implications:

  • Hyponatremia may be a contributing factor in the development of cardiac conduction defects, especially in patients with underlying heart disease.
  • Further research is needed to elucidate the precise role of hyponatremia in cardiac electrophysiology.
  • Clinicians should consider electrolyte balance in patients with cardiac conduction abnormalities.